Arterial Calcifications in Patients with Liver Cirrhosis Are Linked to Hepatic Deficiency of Pyrophosphate Production Restored by Liver Transplantation

Arterial Calcifications in Patients with Liver Cirrhosis Are Linked to Hepatic Deficiency of Pyrophosphate Production Restored by Liver Transplantation

Liver fibrosis is associated with arterial calcification (AC). Since the liver is a source of inorganic pyrophosphate (PPi), an anti-calcifying compound, we investigated the relationship between plasma PPi ([PPi]pl), liver fibrosis, liver function, AC, and the hepatic expression of genes regulating...

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Bibliographic Details
Main Authors: Audrey Laurain, Isabelle Rubera, Micheline Razzouk-Cadet, Stéphanie Bonnafous, Miguel Albuquerque, Valérie Paradis, Stéphanie Patouraux, Christophe Duranton, Olivier Lesaux, Georges Lefthériotis, Albert Tran, Rodolphe Anty, Philippe Gual, Antonio Iannelli, Guillaume Favre
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Biomedicines
Subjects:
arterial calcification
pyrophosphate
liver fibrosis
Online Access:https://www.mdpi.com/2227-9059/10/7/1496

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https://www.mdpi.com/2227-9059/10/7/1496

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