Constitutive Signaling by the Human Cytomegalovirus G Protein Coupled Receptor Homologs US28 and UL33 Enables Trophoblast Migration In Vitro

Human cytomegalovirus (HCMV) encodes four homologs of G protein coupled receptors (vGPCRs), of which two, designated UL33 and US28, signal constitutively. UL33 and US28 are also conserved with chemokine receptors: US28 binds numerous chemokine classes, including the membrane bound chemokine, fractal...

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Bibliographic Details
Main Authors: Nicholas Davis-Poynter, Helen E. Farrell
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/14/2/391