Analysis of CDK12 alterations in a pan‐cancer database

Analysis of CDK12 alterations in a pan‐cancer database

Abstract Background CDK12 inactivation leading to increased neoantigen burden has been hypothesized to sensitize tumors to immune checkpoint inhibition. Pan‐cancer data regarding the frequency of CDK12 alterations are limited. We aimed to characterize CDK12 alterations across all cancer types throug...

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Bibliographic Details
Main Authors: Elizabeth Pan, Angelo Cabal, Juan Javier‐DesLoges, Devin Patel, Justine Panian, Suzanna Lee, Justin Shaya, Taylor Nonato, Xiaojun Xu, Tyler Stewart, Brent Rose, Ahmed Shabaik, Ezra Cohen, Razelle Kurzrock, Pablo Tamayo, Rana R. McKay
Format: Article
Language:English
Published: Wiley 2022-02-01
Series:Cancer Medicine
Subjects:
biomarkers
cancer genetics
clinical cancer research
genomics
Online Access:https://doi.org/10.1002/cam4.4483

Internet

https://doi.org/10.1002/cam4.4483

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