Retinoic acid-gated BDNF synthesis in neuronal dendrites drives presynaptic homeostatic plasticity

Retinoic acid-gated BDNF synthesis in neuronal dendrites drives presynaptic homeostatic plasticity

Homeostatic synaptic plasticity is a non-Hebbian synaptic mechanism that adjusts synaptic strength to maintain network stability while achieving optimal information processing. Among the molecular mediators shown to regulate this form of plasticity, synaptic signaling through retinoic acid (RA) and...

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Bibliographic Details
Main Authors: Shruti Thapliyal, Kristin L Arendt, Anthony G Lau, Lu Chen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-12-01
Series:eLife
Subjects:
homeostatic plasticity
retrograde synaptic signaling
RARα
presynaptic function
Online Access:https://elifesciences.org/articles/79863

Internet

https://elifesciences.org/articles/79863

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