Evaluating the ecological hypothesis: early life salivary microbiome assembly predicts dental caries in a longitudinal case-control study

Evaluating the ecological hypothesis: early life salivary microbiome assembly predicts dental caries in a longitudinal case-control study

Abstract Background Early childhood caries (ECC)—dental caries (cavities) occurring in primary teeth up to age 6 years—is a prevalent childhood oral disease with a microbial etiology. Streptococcus mutans was previously considered a primary cause, but recent research promotes the ecologic hypothesis...

Full description

Bibliographic Details
Main Authors: Freida Blostein, Deesha Bhaumik, Elyse Davis, Elizabeth Salzman, Kerby Shedden, Melissa Duhaime, Kelly M. Bakulski, Daniel W. McNeil, Mary L. Marazita, Betsy Foxman
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Microbiome
Subjects:
Oral microbiome
Early childhood
Ecological hypothesis
Early childhood caries
16S rRNA gene
Whole genome shotgun metagenomics
Online Access:https://doi.org/10.1186/s40168-022-01442-5

Internet

https://doi.org/10.1186/s40168-022-01442-5

Similar Items