Inflammation and Bone Destruction in Arthritis: Synergistic Activity of Immune and Mesenchymal cells in Joints
Rheumatoid arthritis (RA) is an immune-mediated disease of the joints that is characterized by chronic inflammation and synovial hyperplasia that eventually lead to cartilage and bone destruction.Synovial fibroblasts are mesenchymal cells recognized as a key cell population in RA due to their hyperp...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2012-04-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00077/full |