Interaction of Tryptophan- and Arginine-Rich Antimicrobial Peptide with <i>E. coli</i> Outer Membrane—A Molecular Simulation Approach

A short antimicrobial peptide (AMP), rich in tryptophan and arginine (P6—HRWWRWWRR-NH2), was used in molecular dynamics (MD) simulations to investigate the interaction between AMPs and lipopolysaccharides (LPS) from two <i>E. coli</i> outer membrane (OM) membrane models. The OM of Gram-n...

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Bibliographic Details
Main Authors: George Necula, Mihaela Bacalum, Mihai Radu
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/3/2005