Molecular docking as a tool for the discovery of novel insight about the role of acid sphingomyelinase inhibitors in SARS- CoV-2 infectivity

Molecular docking as a tool for the discovery of novel insight about the role of acid sphingomyelinase inhibitors in SARS- CoV-2 infectivity

Abstract Recently, COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its variants, caused > 6 million deaths. Symptoms included respiratory strain and complications, leading to severe pneumonia. SARS-CoV-2 attaches to the ACE-2 receptor of the host cell membrane...

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Bibliographic Details
Main Authors: Samar Sami Alkafaas, Abanoub Mosaad Abdallah, Mai H. Hassan, Aya Misbah Hussien, Sara Samy Elkafas, Samah A. Loutfy, Abanoub Mikhail, Omnia G. Murad, Mohamed I. Elsalahaty, Mohamed Hessien, Rami M. Elshazli, Fatimah A. Alsaeed, Ahmed Ezzat Ahmed, Hani K. Kamal, Wael Hafez, Mohamed T. El-Saadony, Khaled A. El-Tarabily, Soumya Ghosh
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Public Health
Subjects:
Ceramide
Sphingomyelin
FIASMAs
ASMase
COVID-19
Online Access:https://doi.org/10.1186/s12889-024-17747-z

Internet

https://doi.org/10.1186/s12889-024-17747-z

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