<named-content content-type="genus-species">Cryptococcus neoformans</named-content> Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis

<named-content content-type="genus-species">Cryptococcus neoformans</named-content> Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis

ABSTRACT Chitin is an essential component of the cell wall of Cryptococcus neoformans conferring structural rigidity and integrity under diverse environmental conditions. Chitin deacetylase genes encode the enyzmes (chitin deacetylases [Cdas]) that deacetylate chitin, converting it to chitosan. The...

Full description

Bibliographic Details
Main Authors: Rajendra Upadhya, Lorina G. Baker, Woei C. Lam, Charles A. Specht, Maureen J. Donlin, Jennifer K. Lodge
Format: Article
Language:English
Published: American Society for Microbiology 2018-12-01
Series:mBio
Subjects:
chitin deacetylase
catalytic site
cell wall localization
chitosan
metal binding site
fungal virulence
Online Access:https://journals.asm.org/doi/10.1128/mBio.02087-18

Internet

https://journals.asm.org/doi/10.1128/mBio.02087-18

Similar Items