Activation of Cdc42 GTPase upon CRY2-Induced Cortical Recruitment Is Antagonized by GAPs in Fission Yeast

The small GTPase Cdc42 is critical for cell polarization in eukaryotic cells. In rod-shaped fission yeast <i>Schizosaccharomyces pombe</i> cells, active GTP-bound Cdc42 promotes polarized growth at cell poles, while inactive Cdc42-GDP localizes ubiquitously also along cell sides. Zones o...

Full description

Bibliographic Details
Main Authors: Iker Lamas, Nathalie Weber, Sophie G. Martin
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/9/2089