Generation of a homozygous ARHGAP11B knockout hiPSC line by CRISPR/Cas9 system

Generation of a homozygous ARHGAP11B knockout hiPSC line by CRISPR/Cas9 system

The human specific gene ARHGAP11B is preferentially expressed in neural progenitors of fetal neocortex and plays a key role in the evolutionary expansion of the neocortex. Here, we generated a homozygous ARHGAP11B knockout human induced pluripotent stem cell (hiPSC) line through CRISPR/Cas9 gene edi...

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Bibliographic Details
Main Authors: Yu Liu, Yinge Jin, Tao Chen, Yunqin Wu, Xiaohua Peng, Wansheng Li, Shu Wei, Min Chen, Qingjian Zou, Suqin Guo, Jucai Xu, Chengcheng Tang, Xiaoqing Zhou
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506122001131

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http://www.sciencedirect.com/science/article/pii/S1873506122001131

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