Ex vivo infection model for Francisella using human lung tissue

Ex vivo infection model for Francisella using human lung tissue

IntroductionTularemia is mainly caused by Francisella tularensis (Ft) subsp. tularensis (Ftt) and Ft subsp. holarctica (Ftt) in humans and in more than 200 animal species including rabbits and hares. Human clinical manifestations depend on the route of infection and range from flu-like symptoms to s...

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Bibliographic Details
Main Authors: Kristin Köppen, Diana Fatykhova, Gudrun Holland, Jessica Rauch, Dennis Tappe, Mareike Graff, Kerstin Rydzewski, Andreas C. Hocke, Stefan Hippenstiel, Klaus Heuner
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Francisella
intracellular bacteria
human lung
ex vivo
Tularemia
virulence
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1224356/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2023.1224356/full

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