Selected Approaches to Disrupting Protein–Protein Interactions within the MAPK/RAS Pathway

Within the MAPK/RAS pathway, there exists a plethora of protein–protein interactions (PPIs). For many years, scientists have focused efforts on drugging KRAS and its effectors in hopes to provide much needed therapies for patients with <i>KRAS</i>-mutant driven cancers. In this review, w...

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Bibliographic Details
Main Authors: Stephen J. Harwood, Christopher R. Smith, J. David Lawson, John M. Ketcham
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/8/7373