In vitro sperm generation from immature mouse testicular tissue using plasma rich in growth factors

Abstract Background Culture medium enriched with Knockout serum replacement (KSR) can produce in vitro mouse sperm, but it is inefficient, strain-specific and contains bovine products, which limits its use in the human clinic. The study aimed to optimize the culture medium for testicular tissue by u...

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Bibliographic Details
Main Authors: Seyyed Amir Moradian, Mansoureh Movahedin
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-025-04136-5