Alpha-ketoglutarate promotes alveolar bone regeneration by modulating M2 macrophage polarization

Alpha-ketoglutarate promotes alveolar bone regeneration by modulating M2 macrophage polarization

Objectives: Alpha-ketoglutarate (αKG) is an essential metabolite that plays a crucial role in skeletal homeostasis. Here we aim to investigate the effect of αKG on alveolar socket healing and reveal the underlying mechanism in the view of macrophage polarization. Methods: In a murine model pretreate...

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Bibliographic Details
Main Authors: Yuhan Li, Linfeng Liu, Yuyu Li, Wei Song, Bin Shao, Hanwen Li, Weimin Lin, Qiwen Li, Xinxing Shuai, Mingxuan Bai, Bin Zhao, Yuchen Guo, Quan Yuan, Yuan Wang
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Bone Reports
Subjects:
Alpha-ketoglutarate
Alveolar bone
Bone regeneration
Macrophage polarization
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187223000190

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http://www.sciencedirect.com/science/article/pii/S2352187223000190

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