CD16 expression on monocytes in healthy individuals but not schistosome-infected patients is positively associated with levels of parasite-specific IgG and IgG1.

CD16 expression on monocytes in healthy individuals but not schistosome-infected patients is positively associated with levels of parasite-specific IgG and IgG1.

Human IgG1 antibody responses are associated with protection against Schistosoma haematobium infection and are now a target for schistosome vaccine development. This study aimed to investigate the relationship between total IgG and the IgG subclasses and the monocyte IgG receptor, known as FcγRIIIa...

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Bibliographic Details
Main Authors: Laura J Appleby, Norman Nausch, Louise Erskine, Claire D Bourke, Nadine Rujeni, Nicholas Midzi, Takafira Mduluza, Francisca Mutapi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4125298?pdf=render

Internet

http://europepmc.org/articles/PMC4125298?pdf=render

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