Identifying and ranking causal biochemical biomarkers for breast cancer: a Mendelian randomisation study

Identifying and ranking causal biochemical biomarkers for breast cancer: a Mendelian randomisation study

Abstract Background Only a few of the 34 biochemical biomarkers measured in the UK Biobank (UKB) have been associated with breast cancer, with many associations suffering from possible confounding and reverse causation. This study aimed to screen and rank all UKB biochemical biomarkers for possible...

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Bibliographic Details
Main Authors: Sonja N. Tang, Verena Zuber, Konstantinos K. Tsilidis
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Medicine
Subjects:
Mendelian randomisation
Breast cancer
Biomarkers
Instrumental variables
Causal inference
Epidemiology
Online Access:https://doi.org/10.1186/s12916-022-02660-2

Internet

https://doi.org/10.1186/s12916-022-02660-2

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