A Low-Cost Modular Imaging System for Rapid, Multiplexed Immunofluorescence Detection in Clinical Tissues

A Low-Cost Modular Imaging System for Rapid, Multiplexed Immunofluorescence Detection in Clinical Tissues

To image 4-plex immunofluorescence-stained tissue samples at a low cost with cellular level resolution and sensitivity and dynamic range required to detect lowly and highly abundant targets, here we describe a robust, inexpensive (<$9000), 3D printable portable imaging device (Tissue Imager). The...

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Bibliographic Details
Main Authors: Joshua Gu, Hannah Jian, Christine Wei, Jessica Shiu, Anand Ganesan, Weian Zhao, Per Niklas Hedde
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
immunofluorescence
cutaneous T-cell lymphoma
multiplex fluorescence imaging
in situ protein detection
tumor marker profiling
Online Access:https://www.mdpi.com/1422-0067/24/8/7008

Internet

https://www.mdpi.com/1422-0067/24/8/7008

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