Reversal of diabetes following transplantation of an insulin-secreting human liver cell line: Melligen cells

Reversal of diabetes following transplantation of an insulin-secreting human liver cell line: Melligen cells

As an alternative to the transplantation of islets, a human liver cell line has been genetically engineered to reverse type 1 diabetes (TID). The initial liver cell line (Huh7ins) commenced secretion of insulin in response to a glucose concentration of 2.5 mmol/l. After transfection of the Huh7ins c...

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Bibliographic Details
Main Authors: Janet Lawandi, Chang Tao, Binhai Ren, Paul Williams, Dora Ling, M Anne Swan, Najah T Nassif, Fraser R Torpy, Bronwyn A O'Brien, Ann M Simpson
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Molecular Therapy: Methods & Clinical Development
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050116300237

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http://www.sciencedirect.com/science/article/pii/S2329050116300237

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