Development of novel parameters for pathogen identification in clinical metagenomic next-generation sequencing

Development of novel parameters for pathogen identification in clinical metagenomic next-generation sequencing

Introduction: Metagenomic next-generation sequencing (mNGS) has emerged as a powerful tool for rapid pathogen identification in clinical practice. However, the parameters used to interpret mNGS data, such as read count, genus rank, and coverage, lack explicit performance evaluation. In this study, t...

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Bibliographic Details
Main Authors: Xiwen Jiang, Jinghai Yan, Hao Huang, Lu Ai, Xuegao Yu, Pengqiang Zhong, Yili Chen, Zhikun Liang, Wancen Qiu, Huiying Huang, Wenyan Yan, Yan Liang, Peisong Chen, Ruizhi Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Genetics
Subjects:
mNGS
ROC curve
indicators
reads
rank
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1266990/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2023.1266990/full

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