Altered expression of vesicular glutamate transporter-2 and cleaved caspase-3 in the locus coeruleus of nerve-injured rats

Neuropathic pain is a debilitating chronic condition provoked by a lesion in the nervous system and it induces functional alterations to the noradrenergic locus coeruleus (LC), affecting distinct dimensions of pain, like sensorial hypersensitivity, pain-induced depression, and anxiety. However, the...

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Bibliographic Details
Main Authors: Lidia Bravo, Patricia Mariscal, Meritxell Llorca-Torralba, Jose María López-Cepero, Juan Nacher, Esther Berrocoso
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.918321/full