Bis-indole based triazine derivatives: Synthesis, characterization, in vitro β-glucuronidase anti-cancer and anti-bacterial evaluation along with in silico molecular docking and ADME analysis

Bis-indole based triazine derivatives: Synthesis, characterization, in vitro β-glucuronidase anti-cancer and anti-bacterial evaluation along with in silico molecular docking and ADME analysis

The present work described the synthetic procedure adopted for the synthesis of bis-indole-based triazine derivatives via a series of reactions. All the compounds were synthesized through a stepwise reaction. After being confirmation through thin-layer chromatography (TLC) these compounds were chara...

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Bibliographic Details
Main Authors: Shoaib Khan, Wajid Rehman, Fazal Rahim, Rafaqat Hussain, Ahmad J. Obaidullah, Hadil Faris Alotaibi, Mohammed M. Alanazi, Muhammad Usman Khan, Yousaf Khan
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Arabian Journal of Chemistry
Subjects:
Indole
Triazine synthesis
SAR
β-Glucuronidase
Molecular docking & ADME
Online Access:http://www.sciencedirect.com/science/article/pii/S187853522300432X

Internet

http://www.sciencedirect.com/science/article/pii/S187853522300432X

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