Genome-Wide Identification of N6-Methyladenosine Associated SNPs as Potential Functional Variants for Type 1 Diabetes

Genome-Wide Identification of N6-Methyladenosine Associated SNPs as Potential Functional Variants for Type 1 Diabetes

ObjectivesN6-methyladenosine (m6A) is essential in the regulation of the immune system, but the role that its single nucleotide polymorphisms (SNPs) play in the pathogenesis of type 1 diabetes (T1D) remains unknown. This study demonstrated the association between genetic variants in m6A regulators a...

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Bibliographic Details
Main Authors: Yang Chen, Min Shen, Chen Ji, Yanqian Huang, Yun Shi, Li Ji, Yao Qin, Yong Gu, Qi Fu, Heng Chen, Kuanfeng Xu, Tao Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Endocrinology
Subjects:
m6A (N6-methyladenosine)
type 1 diabetes (T1D)
single nucleotide polymorphism
autoimmune disease
intronic variant
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.913345/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.913345/full

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