Systemic analysis of the DNA replication regulator origin recognition complex in lung adenocarcinomas identifies prognostic and expression significance

Abstract Background DNA replication alteration is a hallmark of patients with lung adenocarcinoma (LUAD) and is frequently observed in LUAD progression. Origin recognition complex (ORC) 1, ORC2, ORC3, ORC4, ORC5, and ORC6 form a replication–initiator complex to mediate DNA replication, which plays a...

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Bibliographic Details
Main Authors: Min Tang, Juan Chen, Tian Zeng, Dong‐mei Ye, Yu‐kun Li, Juan Zou, Yu‐ping Zhang
Format: Article
Language:English
Published: Wiley 2023-02-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.5238