Clinical Efficacy of Sarilumab Versus Upadacitinib Over 12 weeks: An Indirect Treatment Comparison

Clinical Efficacy of Sarilumab Versus Upadacitinib Over 12 weeks: An Indirect Treatment Comparison

Abstract Introduction The efficacy of sarilumab and upadacitinib, in combination with disease-modifying antirheumatic drugs (DMARDs), was demonstrated in phase 3 clinical trials of patients with rheumatoid arthritis (RA) refractive to previous biologic DMARDs. In the absence of head-to-head clinical...

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Bibliographic Details
Main Authors: Thomas Huizinga, Ernest Choy, Amy Praestgaard, Hubert van Hoogstraten, Patrick R. LaFontaine, Patricia Guyot, Daniel Aletaha, Ulf Müller-Ladner, Yoshiya Tanaka, Jeffrey R. Curtis, Roy Fleischmann
Format: Article
Language:English
Published: Adis, Springer Healthcare 2023-02-01
Series:Rheumatology and Therapy
Subjects:
Rheumatoid arthritis
Sarilumab
Upadacitinib
Matching-adjusted indirect comparison
Simulated treatment comparison
Online Access:https://doi.org/10.1007/s40744-022-00521-1

Internet

https://doi.org/10.1007/s40744-022-00521-1

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