A Simplified Procedure for Indole Alkaloid Extraction from Catharanthus roseus Combined with a Semi-synthetic Production Process for Vinblastine

A Simplified Procedure for Indole Alkaloid Extraction from Catharanthus roseus Combined with a Semi-synthetic Production Process for Vinblastine

Dried leaves of Catharanthus roseus were extracted with aqueous acidic 0.1 M solution of HCl. Alkaloid-embonate complexes were obtained as precipitates by treating the extract with an alkaline (NaOH) solution of embonic acid (4,4-methylene-bis-3-hydroxynaphtalenecarboxylic acid). The precipitate mai...

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Bibliographic Details
Main Authors: Marja-Liisa Riekkola, Aarre Huhtikangas, Tuulikki Seppänen-Laakso, Into Laakso, Arvind Verma
Format: Article
Language:English
Published: MDPI AG 2007-07-01
Series:Molecules
Subjects:
Indole alkaloids
vinblastine
semi-synthesis
mass spectrometry
electrospray ionization.
Online Access:http://www.mdpi.com/1420-3049/12/7/1307/

Internet

http://www.mdpi.com/1420-3049/12/7/1307/

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