Thymoquinone Radiosensitizes Human Colorectal Cancer Cells in 2D and 3D Culture Models

Thymoquinone Radiosensitizes Human Colorectal Cancer Cells in 2D and 3D Culture Models

Resistance of cancer cells and normal tissue toxicity of ionizing radiation (IR) are known to limit the success of radiotherapy. There is growing interest in using IR with natural compounds to sensitize cancer cells and spare healthy tissues. Thymoquinone (TQ) was shown to radiosensitize several can...

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Bibliographic Details
Main Authors: Samar Al Bitar, Farah Ballout, Alissar Monzer, Mariam Kanso, Nour Saheb, Deborah Mukherji, Walid Faraj, Ayman Tawil, Samer Doughan, Maher Hussein, Wassim Abou-Kheir, Hala Gali-Muhtasib
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cancers
Subjects:
colorectal cancer
cancer stem cells
patient-derived organoids
colon spheres
radiosensitization
DNA repair
Online Access:https://www.mdpi.com/2072-6694/14/6/1363

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https://www.mdpi.com/2072-6694/14/6/1363

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