Cytochalasin B triggers a novel pertussis toxin sensitive pathway in TNF-alpha primed neutrophils

Cytochalasin B triggers a novel pertussis toxin sensitive pathway in TNF-alpha primed neutrophils

<p>Abstract</p> <p>Background</p> <p>Cytochalasin B does not directly activate the oxygen-radical-producing NADPH oxidase activity of neutrophils but transfers desensitized G-protein coupled receptors (GPCR) into an active signaling state by uncoupling GCPR from the cyt...

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Bibliographic Details
Main Authors: Mellqvist Ulf-Henrik, Fu Huamei, Pellmé Sara, Bylund Johan, Hellstrand Kristoffer, Karlsson Anna, Dahlgren Claes
Format: Article
Language:English
Published: BMC 2004-05-01
Series:BMC Cell Biology
Subjects:
cytokines
superoxide
priming
TNF
cytoskeleton
receptor reactivation
pertussis toxin
G. protein
GPCR
NADPH-oxidase
Online Access:http://www.biomedcentral.com/1471-2121/5/21

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http://www.biomedcentral.com/1471-2121/5/21

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