Effects of rAAV‐mediated FGF‐2 gene transfer and overexpression upon the chondrogenic differentiation processes in human bone marrow aspirates

Effects of rAAV‐mediated FGF‐2 gene transfer and overexpression upon the chondrogenic differentiation processes in human bone marrow aspirates

Abstract Background Application of genetically modified bone marrow concentrates in articular cartilage lesions is a promising approach to enhance cartilage repair by stimulating the chondrogenic differentiation processes in sites of injury. Method In the present study, we examined the potential ben...

Full description

Bibliographic Details
Main Authors: Janina Frisch, Jagadeesh K. Venkatesan, Ana Rey‐Rico, Adam M. Zawada, Gertrud Schmitt, Henning Madry, Magali Cucchiarini
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Journal of Experimental Orthopaedics
Subjects:
Cartilage repair
Gene therapy
Human bone marrow aspirates
rAAV
FGF‐2
Online Access:https://doi.org/10.1186/s40634-016-0052-6

Internet

https://doi.org/10.1186/s40634-016-0052-6

Similar Items