Generation of a new human induced pluripotent stem cell (hiPSC) line from a South Asian Indian with a MYBPC3Δ25bp variant

Myosin binding protein C3 (MYBPC3) is a thick filament contractile protein that interacts with myosin, titin and actin and regulates cardiac muscle contraction. Genetic variations in the MYBPC3 gene are known causal factors for cardiomyopathy and heart failure. Previously, we identified a recurrent...

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Bibliographic Details
Main Authors: Prasanth Chimata, Deepak K Kashyap, Thiagarajan Sairam, Akshayaa Ganesh, Kumarasamy Thangaraj, Meera Purushottam, Biju Viswanath, Sanjeev Jain, Perundurai S Dhandapany
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506122003270