Alzheimer and Parkinson diseases, frontotemporal lobar degeneration and amyotrophic lateral sclerosis overlapping neuropathology start in the first two decades of life in pollution exposed urbanites and brain ultrafine particulate matter and industrial nanoparticles, including Fe, Ti, Al, V, Ni, Hg, Co, Cu, Zn, Ag, Pt, Ce, La, Pr and W are key players. Metropolitan Mexico City health crisis is in progress

The neuropathological hallmarks of Alzheimer’s disease (AD), Parkinson’s disease (PD), frontotemporal lobar degeneration (FTLD), and amyotrophic lateral sclerosis (ALS) are present in urban children exposed to fine particulate matter (PM2.5), combustion and friction ultrafine PM (UFPM), and industri...

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Main Authors: Lilian Calderón-Garcidueñas, Elijah W. Stommel, Ricardo Torres-Jardón, Jacqueline Hernández-Luna, Mario Aiello-Mora, Angélica González-Maciel, Rafael Reynoso-Robles, Beatriz Pérez-Guillé, Héctor G. Silva-Pereyra, Samuel Tehuacanero-Cuapa, Arturo Rodríguez-Gómez, Ingolf Lachmann, Carolina Galaz-Montoya, Richard L. Doty, Anik Roy, Partha S. Mukherjee
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Human Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnhum.2023.1297467/full