Lipoic Acid Metabolism as a Potential Chemotherapeutic Target Against Plasmodium falciparum and Staphylococcus aureus

Lipoic Acid Metabolism as a Potential Chemotherapeutic Target Against Plasmodium falciparum and Staphylococcus aureus

Lipoic acid (LA) is an organic compound that plays a key role in cellular metabolism. It participates in a posttranslational modification (PTM) named lipoylation, an event that is highly conserved and that occurs in multimeric metabolic enzymes of very distinct microorganisms such as Plasmodium sp....

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Bibliographic Details
Main Authors: Sun Liu Rei Yan, Felipe Wakasuqui, Xiaochen Du, Matthew R. Groves, Carsten Wrenger
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Chemistry
Subjects:
Lipoic acid
malaria
protein lipoylation
Plasmodium
S. aureus
Lipoic acid (LA)
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.742175/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2021.742175/full

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