Dietary methanol regulates human gene activity.

Dietary methanol regulates human gene activity.

Methanol (MeOH) is considered to be a poison in humans because of the alcohol dehydrogenase (ADH)-mediated conversion of MeOH to formaldehyde (FA), which is toxic. Our recent genome-wide analysis of the mouse brain demonstrated that an increase in endogenous MeOH after ADH inhibition led to a signif...

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Bibliographic Details
Main Authors: Anastasia V Shindyapina, Igor V Petrunia, Tatiana V Komarova, Ekaterina V Sheshukova, Vyacheslav S Kosorukov, Gleb I Kiryanov, Yuri L Dorokhov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4102594?pdf=render

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http://europepmc.org/articles/PMC4102594?pdf=render

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