The effects of chitosan-loaded JQ1 nanoparticles on OVCAR-3 cell cycle and apoptosis-related gene expression

The effects of chitosan-loaded JQ1 nanoparticles on OVCAR-3 cell cycle and apoptosis-related gene expression

Background and purpose: Ovarian cancer is the deadliest gynecological cancer. Bromodomain and extra terminal domain (BET) proteins play major roles in the regulation of gene expression at the epigenetic level. Jun Qi (JQ1) is a potent inhibitor of BET proteins. Regarding the short half-life and poor...

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Bibliographic Details
Main Authors: Ehsan Masoudi, Mitra Soleimani, Giti Zarinfard, Mansour Homayoun, Mohammad Bakhtiari
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
chitosan; jq1; nanoparticles; ovarian cancer.
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2024;volume=19;issue=1;spage=53;epage=63;aulast=Masoudi

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http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2024;volume=19;issue=1;spage=53;epage=63;aulast=Masoudi

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