Urokinase-type plasminogen activator (uPA) regulates invasion and matrix remodelling in colorectal cancer

Background: Cancer cells remodel their local physical environment through processes of matrix reorganisation, deposition, stiffening and degradation. Urokinase-type plasminogen activator (uPA), which is encoded by the PLAU gene, is an extracellular proteolytic enzyme known to be involved in cancer p...

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Bibliographic Details
Main Authors: Auxtine Micalet, Luke J. Tappouni, Katarzyna Peszko, Despoina Karagianni, Ashley Lam, John R. Counsell, Sergio A. Quezada, Emad Moeendarbary, Umber Cheema
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Matrix Biology Plus
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590028523000108