Urokinase-type plasminogen activator (uPA) regulates invasion and matrix remodelling in colorectal cancer
Background: Cancer cells remodel their local physical environment through processes of matrix reorganisation, deposition, stiffening and degradation. Urokinase-type plasminogen activator (uPA), which is encoded by the PLAU gene, is an extracellular proteolytic enzyme known to be involved in cancer p...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-12-01
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Series: | Matrix Biology Plus |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2590028523000108 |