Sm16, A Schistosoma mansoni Immunomodulatory Protein, Fails to Elicit a Protective Immune Response and Does Not Have an Essential Role in Parasite Survival in the Definitive Host

Sm16 is an immunomodulatory protein that seems to play a key role in the suppression of the cutaneous inflammatory response during Schistosoma mansoni penetration of the skin of definitive hosts. Therefore, Sm16 represents a potential target for protective immune responses induced by vaccination. In...

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Bibliographic Details
Main Authors: Wilma Patrícia de Oliveira Santos Bernardes, Juliano Michel de Araújo, Gardênia Braz Carvalho, Clarice Carvalho Alves, Aline Thaynara de Moura Coelho, Isabela Thamara Sabino Dutra, Sueleny Silva Ferreira Teixeira, Rosy Iara Maciel de Azambuja Ribeiro, Marina de Moraes Mourão, Rosiane Aparecida da Silva-Pereira, Cristina Toscano Fonseca
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2019/6793596