Isoform specific gene expression analysis of KRAS in the prognosis of lung adenocarcinoma patients

Isoform specific gene expression analysis of KRAS in the prognosis of lung adenocarcinoma patients

Abstract Background Aberrant mutations in KRAS play a critical role in tumor initiation and progression, and are a negative prognosis factor in lung adenocarcinoma (LUAD). Results Using genomic analysis for K-Ras isoforms (K-Ras4A and K-Ras4B) and large-scale multi-omics data, we inspected the overa...

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Bibliographic Details
Main Authors: In Seok Yang, Sangwoo Kim
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Bioinformatics
Subjects:
Isoform specific expression
KRAS mutation
K-Ras4A
Lung adenocarcinoma
Survival
Online Access:http://link.springer.com/article/10.1186/s12859-018-2011-y

Internet

http://link.springer.com/article/10.1186/s12859-018-2011-y

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