Pericyte-derived cells participate in optic nerve scar formation

Pericyte-derived cells participate in optic nerve scar formation

Introduction: Pericytes (PCs) are specialized cells located abluminal of endothelial cells on capillaries, fulfilling numerous important functions. Their potential involvement in wound healing and scar formation is achieving increasing attention since years. Thus, many studies investigated the parti...

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Main Authors: Julia Preishuber-Pflügl, Daniela Mayr, Veronika Altinger, Susanne M. Brunner, Andreas Koller, Christian Runge, Anja-Maria Ladek, Markus Lenzhofer, Francisco J. Rivera, Herbert Tempfer, Ludwig Aigner, Herbert A. Reitsamer, Andrea Trost
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Physiology
Subjects:
pericyte
inducible PDGFRβ-P2A-CreERT2-tdTomato lineage tracing reporter mouse
fibrotic cells
optic nerve crush
scar formation
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1151495/full

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https://www.frontiersin.org/articles/10.3389/fphys.2023.1151495/full

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