Human organoids are superior to cell culture models for intestinal barrier research

Human organoids are superior to cell culture models for intestinal barrier research

Loss of intestinal epithelial barrier function is a hallmark in digestive tract inflammation. The detailed mechanisms remain unclear due to the lack of suitable cell-based models in barrier research. Here we performed a detailed functional characterization of human intestinal organoid cultures under...

Full description

Bibliographic Details
Main Authors: Catherine Kollmann, Hannah Buerkert, Michael Meir, Konstantin Richter, Kai Kretzschmar, Sven Flemming, Matthias Kelm, Christoph-Thomas Germer, Christoph Otto, Natalie Burkard, Nicolas Schlegel
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
intestinal epithelial barrier
Caco2 cells
intestinal organoids
enteroids
gut barrier
inflammatory cell model
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1223032/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2023.1223032/full

Similar Items