Induced Pluripotent Stem Cell-Derived Neural Precursors Improve Memory, Synaptic and Pathological Abnormalities in a Mouse Model of Alzheimer’s Disease

Induced Pluripotent Stem Cell-Derived Neural Precursors Improve Memory, Synaptic and Pathological Abnormalities in a Mouse Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common type of dementia in the elderly population. The disease is characterized by progressive memory loss, cerebral atrophy, extensive neuronal loss, synaptic alterations, brain inflammation, extracellular accumulation of amyloid-β (Aβ) plaques, and intracellula...

Full description

Bibliographic Details
Main Authors: Enrique Armijo, George Edwards, Andrea Flores, Jorge Vera, Mohammad Shahnawaz, Fabio Moda, Cesar Gonzalez, Magdalena Sanhueza, Claudio Soto
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
stem cells
therapy
Alzheimer’s disease
amyloid-beta
tau
inflammation
Online Access:https://www.mdpi.com/2073-4409/10/7/1802

Internet

https://www.mdpi.com/2073-4409/10/7/1802

Similar Items