The Primary Enveloped Virion of Herpes Simplex Virus 1: Its Role in Nuclear Egress

ABSTRACT Many viruses migrate between different cellular compartments for successive stages of assembly. The HSV-1 capsid assembles in the nucleus and then transfers into the cytoplasm. First, the capsid buds through the inner nuclear membrane, becoming coated with nuclear egress complex (NEC) prote...

Full description

Bibliographic Details
Main Authors: William W. Newcomb, Juan Fontana, Dennis C. Winkler, Naiqian Cheng, J. Bernard Heymann, Alasdair C. Steven
Format: Article
Language:English
Published: American Society for Microbiology 2017-07-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.00825-17