LASS2 suppresses metastasis in multiple cancers by regulating the ferroptosis signalling pathway through interaction with TFRC

LASS2 suppresses metastasis in multiple cancers by regulating the ferroptosis signalling pathway through interaction with TFRC

Abstract Background As a key enzyme in ceramide synthesis, longevity assurance homologue 2 (LASS2) has been indicated to act as a tumour suppressor in a variety of cancers. Ferroptosis is involved in a variety of tumour processes; however, the role of LASS2 in regulating ferroptosis has yet to be ex...

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Bibliographic Details
Main Authors: Yunfei Huang, Jie Du, Dan Li, Wei He, Zhouheng Liu, Li Liu, Xiaoli Yang, Xiaoming Cheng, Rui Chen, Yan Yang
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Cancer Cell International
Subjects:
LASS2
TFRC
Ferroptosis
Multiple cancers
Metastasis
Online Access:https://doi.org/10.1186/s12935-024-03275-8

Internet

https://doi.org/10.1186/s12935-024-03275-8

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