NF-κB in monocytes and macrophages – an inflammatory master regulator in multitalented immune cells

Nuclear factor κB (NF-κB) is a dimeric transcription factor constituted by two of five protein family members. It plays an essential role in inflammation and immunity by regulating the expression of numerous chemokines, cytokines, transcription factors, and regulatory proteins. Since NF-κB is expres...

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Bibliographic Details
Main Authors: Marion Mussbacher, Martina Derler, José Basílio, Johannes A. Schmid
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1134661/full