Toxoplasma gondii relies on both host and parasite isoprenoids and can be rendered sensitive to atorvastatin.

Intracellular pathogens have complex metabolic interactions with their host cells to ensure a steady supply of energy and anabolic building blocks for rapid growth. Here we use the obligate intracellular parasite Toxoplasma gondii to probe this interaction for isoprenoids, abundant lipidic compounds...

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Bibliographic Details
Main Authors: Zhu-Hong Li, Srinivasan Ramakrishnan, Boris Striepen, Silvia N J Moreno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3798403?pdf=render