Toxoplasma gondii relies on both host and parasite isoprenoids and can be rendered sensitive to atorvastatin.
Intracellular pathogens have complex metabolic interactions with their host cells to ensure a steady supply of energy and anabolic building blocks for rapid growth. Here we use the obligate intracellular parasite Toxoplasma gondii to probe this interaction for isoprenoids, abundant lipidic compounds...
Main Authors: | Zhu-Hong Li, Srinivasan Ramakrishnan, Boris Striepen, Silvia N J Moreno |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC3798403?pdf=render |
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