Cav1.2 channels mediate persistent chronic stress-induced behavioral deficits that are associated with prefrontal cortex activation of the p25/Cdk5-glucocorticoid receptor pathway

Chronic stress is known to precipitate and exacerbate neuropsychiatric symptoms, and exposure to stress is particularly pathological in individuals with certain genetic predispositions. Recent genome wide association studies have identified single nucleotide polymorphisms (SNPs) in the gene CACNA1C,...

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Bibliographic Details
Main Authors: Charlotte C. Bavley, Delaney K. Fischer, Bryant K. Rizzo, Anjali M. Rajadhyaksha
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Neurobiology of Stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289516300443