Error and error mitigation in low-coverage genome assemblies.
The recent release of twenty-two new genome sequences has dramatically increased the data available for mammalian comparative genomics, but twenty of these new sequences are currently limited to ∼2× coverage. Here we examine the extent of sequencing error in these 2× assemblies, and its potential im...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-02-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3038916?pdf=render |