Molecular Mechanisms Underlying Ca<sup>2+</sup>/Calmodulin-Dependent Protein Kinase Kinase Signal Transduction

Ca<sup>2+</sup>/calmodulin-dependent protein kinase kinase (CaMKK) is the activating kinase for multiple downstream kinases, including CaM-kinase I (CaMKI), CaM-kinase IV (CaMKIV), protein kinase B (PKB/Akt), and 5′AMP-kinase (AMPK), through the phosphorylation of their activation-loop T...

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Bibliographic Details
Main Authors: Hiroshi Tokumitsu, Hiroyuki Sakagami
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/19/11025