Ilimaquinone Induces Apoptosis and Autophagy in Human Oral Squamous Cell Carcinoma Cells

Ilimaquinone Induces Apoptosis and Autophagy in Human Oral Squamous Cell Carcinoma Cells

In this study, the anti-tumor activity of ilimaquinone (IQ), a sesquiterpene quinone isolated from marine sponge <i>Halichondria</i> sp., in oral squamous cell carcinoma (OSCC) cells, was investigated. IQ suppressed the viability of the OSCC cell lines SCC4 and SCC2095 with IC<sub>...

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Bibliographic Details
Main Authors: Cheng-Wen Lin, Li-Yuan Bai, Jui-Hsin Su, Chang-Fang Chiu, Wei-Yu Lin, Wei-Ting Huang, Ming-Cheng Shih, Yu-Ting Huang, Jing-Lan Hu, Jing-Ru Weng
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Biomedicines
Subjects:
ilimaquinone
OSCC
autophagy
apoptosis
p53
Online Access:https://www.mdpi.com/2227-9059/8/9/296

Internet

https://www.mdpi.com/2227-9059/8/9/296

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