Network- and enrichment-based inference of phenotypes and targets from large-scale disease maps
Abstract Complex diseases are inherently multifaceted, and the associated data are often heterogeneous, making linking interactions across genes, metabolites, RNA, proteins, cellular functions, and clinically relevant phenotypes a high-priority challenge. Disease maps have emerged as knowledge bases...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-04-01
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Series: | npj Systems Biology and Applications |
Online Access: | https://doi.org/10.1038/s41540-022-00222-z |